An Outbreak of Tri-ortho-cresyl Phosphate (T.O.C.P.) Poisoning in Durban

An outbreak of tri-ortho-cresyl phosphate (T.O.C.P.) poisoning in Durban.

Tri-ortho-cresyl phosphate (T.O.C.P.) is an organic phosphorus compound commonly used in industry as a plasticizer, and is so used in the manufacture of lacquers, dopes, synthetic fabrics, and synthetic lignin resin; it is used as a water-proofing agent in textile manufacture. It is said to be an excellent grinding medium for pigments; it is also used in making polyvinyl chloride sheeting and f...

Interim Specific Ground Water Criterion - Tri-ortho-cresyl phosphate (TOCP)

[A case of tri-ortho-cresyl-phosphate poisoning].

Electron Microscopic Study of Acute Neurotoxicity of Tocp(tri Ortho Cresyl Phosphate) of Sciatic Nerve in Adult Hen

In acute neurotoxicity of TOCP of sciatic nerve there was more neurotic changes as degenerate myelin fibers in comparsm with few changes in the spinal cord. The study was done on 2 groups of adult hen, each group consist of 20 adult hen, 20 untreated control as single dosed orally with corn oil. Treated group of 20 adult hen dosed orally with 500mg/kg TOCP in corn oil as single dose. The experi...

Changes of mitochondrial ultrastructures and function in central nervous tissue of hens treated with tri-ortho-cresyl phosphate (TOCP).

Tri-ortho-cresyl phosphate (TOCP), an organophosphorus ester, is capable of producing organophosphorus ester-induced delayed neurotoxicity (OPIDN) in humans and sensitive animals. The mechanism of OPIDN has not been fully understood. The present study has been designed to evaluate the role of mitochondrial dysfunctions in the development of OPIDN. Adult hens were treated with 750 mg/kg·bw TOCP ...